Are you a Healthcare Professional?
The information contained in this section of the website is intended for US healthcare professionals only. Click YES to confirm that you are a healthcare professional.
R.A.R.E. PATIENT SUPPORT PROGRAM HELPS YOU EVERY STEP OF THE WAY
Providing you with support, encouragement, and the appropriate tools and information, the Recordati Rare Diseases R.A.R.E. program helps you manage the many aspects of your treatment.
Once you are prescribed ISTURISA, you are automatically eligible for the R.A.R.E. program services.
INSURANCE AND FINANCIAL ASSISTANCE
Our reimbursement team may help with:
- Navigating insurance processes, like Prior Authorization and Appeal
- Investigating your insurance benefits
- Understanding co-pay assistance (for eligible, insured patients) and identifying other financial assistance optionsa
RECEIVING YOUR MEDICINE
Our trained pharmacy team may help with:
- Making sure that your medicine arrives on time (overnight delivery)
- Any questions you have about starting treatment with ISTURISA
- 24/7 pharmacy support is also available
EDUCATION
Our R.A.R.E. clinical Nurse Educators will:
- Check in with you periodically and answer any questions you may have about ISTURISA
Information provided by the Nurse Educators is for educational purposes only and is not intended to replace the advice of your healthcare provider.
CO-PAY PROGRAM
Recordati Rare Diseases offers a $20 co-pay for qualified patients with commercial insurance.a
Eligibility requirements, restrictions and limitations apply.
The R.A.R.E. Patient Support Program is administered in partnership with our specialty pharmacy.
YOUR R.A.R.E. SUPPORT TEAM
Your R.A.R.E. support team is here for you right from the start.
Our knowledgeable and reliable professionals have been fully trained about ISTURISA, and are dedicated to supporting your treatment goals. Your team includes:
INSURANCE SPECIALISTS
to help get you the best
coverage for your medications.
PHARMACISTS
who are available to you 24/7, every
day of the year.
NURSE EDUCATORS
to answer your questions and
support you during treatment.b
PATIENT LIAISONS
to be there for you throughout
your journey.
Information provided by the Nurse Educators is for educational purposes only and not intended to replace the advice of your healthcare provider.
Our team will stay in touch throughout your therapy
Your enrollment in R.A.R.E. will be processed along with your prescription. However, if you have any questions, or would like to discuss how the program can help support your treatment, give us a call.
CONNECT WITH A PATIENT LIAISON (PL)
Your health journey is uniquely your own, but you're not alone. As part of the R.A.R.E. family, you have access to a Recordati Rare Diseases PL to help you with your treatment along the way.
When you opt in, your PLc will be there to:
- Provide additional disease state education
- Answer questions about your medicine
- Connect to additional resources regarding the disease state
- Listen with an empathetic ear
These services are provided at no additional cost to you by Recordati Rare Diseases. Information provided by the PL program is for educational purposes only and is not intended to replace the care and advice of your healthcare providers.
To get started, complete the Program Enrollment Opt-In Form
Learn more about the R.A.R.E. Patient Support Program
ISTURISA helped me start a new chapter in my life.
—Andrea, an ISTURISA Patient Ambassador who has been living with Cushing’s disease since 1996
WHAT IS ISTURISA?
ISTURISA (osilodrostat) is a prescription medicine used to treat elevated levels of cortisol in the blood (endogenous hypercortisolemia) in adults with Cushing’s syndrome:
- who cannot have surgery, or
- who have had surgery which did not cure their Cushing’s syndrome
It is not known if ISTURISA is safe and effective in children.
ISTURISA is a prescription medicine used to treat elevated levels of cortisol in the blood (known as endogenous hypercortisolemia) in adults with Cushing’s syndrome. Appropriate patients either cannot have surgery, or have had surgery which did not cure their Cushing’s syndrome. It is not known if ISTURISA is safe and effective in children.
IMPORTANT SAFETY INFORMATION
Before starting ISTURISA tell your healthcare provider about all your medical conditions, including if you:
- have or had heart problems, such as an irregular heartbeat, including a condition called prolonged QT syndrome (QT interval prolongation). Your healthcare provider will check the electrical signal of your heart (called an electrocardiogram) before you start taking ISTURISA, 1 week after starting ISTURISA, and as needed after that.
- have a history of low levels of potassium or magnesium in your blood.
- have liver problems.
- are or plan to become pregnant. It is not known if ISTURISA will harm your unborn baby. There are risks to the mother and unborn baby associated with active Cushing’s syndrome during pregnancy.
- are breastfeeding or plan to breastfeed. It is not known if ISTURISA passes into your breast milk. You should not breastfeed if you take ISTURISA and for 1 week after stopping treatment.
Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.
Especially tell your healthcare provider if you take medicines used to treat certain heart problems. Ask your healthcare provider if you are not sure whether your medicine is used to treat heart problems.
ISTURISA can cause serious side effects including:
-
Low cortisol levels in your blood (hypocortisolism). Tell your healthcare provider right away if you experience any of the following symptoms, as these may be symptoms of very low cortisol level, known as adrenal insufficiency: nausea, vomiting, tiredness (fatigue), low blood pressure, problems with body salt (electrolyte) levels in your blood, stomach (abdominal) pain, loss of appetite, dizziness, low blood sugar.
If you get symptoms of hypocortisolism while taking ISTURISA, your healthcare provider may change your dose or ask you to stop taking it.
- Heart problem or a heart rhythm problem, such as an irregular heartbeat which could be a sign of a heart problem called QT prolongation. Call your healthcare provider right away if you have irregular heartbeats.
-
Increase in other adrenal hormone levels. Your other adrenal hormones may increase when you take ISTURISA. Your healthcare provider may monitor you for the symptoms associated with these hormonal changes while you are taking ISTURISA:
- Low potassium (hypokalemia)
- High blood pressure (hypertension)
- Swelling (edema) in the legs, ankles or other signs of fluid retention
- Excessive facial or body hair growth (hirsutism)
- Acne (in women)
Call your healthcare provider if you have any of these side effects.
The most common side effects of ISTURISA include very low cortisol levels (adrenal insufficiency), tiredness (fatigue), nausea, headache, and swelling of the legs, ankles or other signs of fluid retention (edema), decreased appetite, pain in your joints (arthralgia), muscle pain or soreness (myalgia), weakness (asthenia), and diarrhea.
These are not all the possible side effects of ISTURISA. Call your healthcare provider for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Call 1-800-FDA-1088 or visit www.fda.gov/medwatch.
ISTURISA® (osilodrostat) tablets, for oral use, is available as 1 mg and 5 mg tablets.
Please see full Prescribing Information.
PP-IST-US-0576
You are about to leave the ISTURISA.com website and enter a website operated by an independent third party. The links to third-party websites contained on ISTURISA.com are provided solely for your convenience. Recordati Rare Diseases does not control the opinions, claims or comments contained on any third-party website linked to ISTURISA.com, and your activities at those websites will be governed by the policies and practices of those third parties.
Considering ISTURISA? Stay informed. Stay empowered.
Sign up to get helpful information about Cushing’s syndrome (CS), how ISTURISA works, and what to expect if it's prescribed. You'll also receive:
Real
patient stories
Tips
and resources for managing CS with ISTURISA
Encouragement
and support
