FOR PATIENT SUPPORT, PLEASE CALL 1-888-855-RARE (7273)

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Stay informed, connected, and supported

The R.A.R.E.® program may help with financial assistance and more

RARE Patient Support Program Logo

Recordati Rare Diseases created the R.A.R.E. Patient Support Program to help you every step of the way.

It is our goal to provide you with support, encouragement, and the appropriate tools and information to help you manage the many aspects of your treatment.

Once you are prescribed ISTURISA® (osilodrostat), you are automatically enrolled in the R.A.R.E. program.

Insurance and Financial Assistance

INSURANCE AND FINANCIAL ASSISTANCE

Our reimbursement team may help with:

  • Navigating insurance processes, like Prior Authorization and Appeal
  • Investigating your insurance benefits
  • Understanding co-pay assistance (for eligible, insured patients) and identifying other financial assistance optionsa
Receiving Your Medicine

Receiving Your Medicine

Our trained pharmacy team may help with:

  • Making sure that your medicine arrives on time (overnight delivery)
  • Any questions you have about starting treatment with ISTURISA

24/7 pharmacy support is also available.

Education

Education

Our R.A.R.E. clinical Nurse Educators will:

  • Check in with you periodically and answer any questions you may have about ISTURISA

Information provided by the Nurse Educators is for educational purposes only and is not intended to replace the advice of your healthcare provider.

Co-Pay Program

Recordati Rare Diseases offers a $20 co-pay for qualified patients with commercial insurance.a

a Eligibility requirements, restrictions and limitations apply.

The R.A.R.E. Patient Support Program is administered in partnership with our specialty pharmacy.

Contact the R.A.R.E. Patient Support Program for Assistance

Monday-Friday between 8:00 AM and 8:00 PM ET:
Phone: 1‑888‑855‑RARE (7273)
A pharmacist is always available.

YOUR R.A.R.E. SUPPORT TEAM

Your R.A.R.E. support team is here for you right from the start

Our knowledgeable and reliable professionals have been fully trained about ISTURISA, and are dedicated to supporting your treatment goals. Your team includes

Your support team: An Insurance Specialist

INSURANCE SPECIALISTS to help get you the best coverage for your medications

Your support team: Pharmacists

PHARMACISTS who are available to you 24/7, every day of the year

Your support team: Nurse Educators

NURSE EDUCATORS to answer your questions and support you during treatmentb

bInformation provided by the Nurse Educators is for educational purposes only and not intended to replace the advice of your healthcare provider.

Our team will stay in touch throughout your therapy

Your enrollment in R.A.R.E. will be processed along with your prescription. However, if you have any questions, or would like to discuss how the program can help support your treatment, give us a call.

ISTURISA helped me start a new chapter in my life.

-Andrea, an ISTURISA Patient Ambassador who has been living with Cushing's disease since 1996

CONNECT WITH A PATIENT LIAISON (PL)

Your health journey is uniquely your own, but you’re not alone. As part of the Recordati Access, Resources, and Engagement (R.A.R.E.®) family, you have access to a Recordati Rare Diseases PL to help you with your treatment along the way.

To get started, complete the Program Enrollment Opt-In Form

COMPLETE THE OPT-IN FORM

When you opt in, your PLc will be there to:

  • Provide additional disease state education
  • Answer questions about your medicine
  • Connect to additional resources regarding the disease state
  • Listen with an empathetic ear
cThese services are provided at no additional cost to you by Recordati Rare Diseases. Information provided by the PL program is for educational purposes only and is not intended to replace the care and advice of your healthcare providers.
See our brochure for more information on our savings, access, and support.

Learn more about the R.A.R.E. Patient Support Program

Download the R.A.R.E. Brochure
Learn how the dose of ISTURISA is personalized for your specific needs More about individualized dosing Discover more helpful resources from ISTURISA and R.A.R.E. Resources to support your treatment goals

INDICATION(S) AND IMPORTANT SAFETY INFORMATION

WHAT is ISTURISA?

ISTURISA (osilodrostat) is a prescription medicine that is used to treat adults with Cushing’s disease:

  • who cannot have pituitary surgery, or
  • who have had pituitary surgery, but the surgery did not cure their Cushing’s disease

It is not known if ISTURISA is safe and effective in children.

INDICATION(S) AND IMPORTANT SAFETY INFORMATION

WHAT is ISTURISA?

ISTURISA (osilodrostat) is a prescription medicine that is used to treat adults with Cushing’s disease:

  • who cannot have pituitary surgery, or
  • who have had pituitary surgery, but the surgery did not cure their Cushing’s disease

It is not known if ISTURISA is safe and effective in children.

IMPORTANT SAFETY INFORMATION

Before starting ISTURISA tell your healthcare provider about all your medical conditions, including if you:

  • have or had heart problems, such as an irregular heartbeat, including a condition called prolonged QT syndrome (QT internal prolongation). Your healthcare provider will check the electrical signal of your heart (called an electrocardiogram) before you start taking ISTURISA, 1 week after starting ISTURISA, and as needed after that.
  • have a history of low levels of potassium or magnesium in your blood.
  • have liver problems.
  • are breastfeeding or plan to breastfeed. It is not known if ISTURISA passes into your breast milk. You should not breastfeed if you take ISTURISA and for 1 week after stopping treatment.

Tell your healthcare provider about all the medicines you take, including any prescription and over-the-counter medicines, vitamins, or herbal supplements.

Especially tell your healthcare provider if you take medicines used to treat certain heart problems. Ask your healthcare provider if you are not sure whether your medicine is used to treat heart problems.

ISTURISA can cause serious side effects including:

  • Low cortisol levels in your blood (hypocortisolism). Tell your healthcare provider right away if you experience more than one of the following symptoms, as these may be symptoms of very low cortisol level, known as adrenal insufficiency: nausea, vomiting, tiredness (fatigue), low blood pressure, stomach (abdominal) pain, loss of appetite, dizziness.

    If you get symptoms of hypocortisolism while taking ISTURISA, your healthcare provider may change your dose or ask you to stop taking it.

  • Heart problem or a heart rhythm problem, such as an irregular heartbeat which could be a sign of a heart problem called QT prolongation. Call your healthcare provider right away if you have irregular heartbeats.

  • Increase in other adrenal hormone levels. Your other adrenal hormones may increase when you take ISTURISA. Your healthcare provider may monitor you for the symptoms associated with these hormonal changes while you are taking ISTURISA:

    • Low potassium (hypokalemia).
    • High blood pressure (hypertension).
    • Swelling (edema) in the legs, ankles or other signs of fluid retention.
    • Excessive facial or body hair growth (hirsutism).
    • Acne (in women).

Call your healthcare provider if you have any of these side effects.

The most common side effects of ISTURISA include very low cortisol levels (adrenal insufficiency), tiredness (fatigue), nausea, headache, and swelling of the legs, ankles or other signs of fluid retention (edema).

These are not all the possible side effects of ISTURISA. Call your healthcare provider for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Call 1-800-FDA-1088 or visit www.fda.gov/medwatch.

ISTURISA® (osilodrostat) tablets, for oral use, is available as 1 mg and 5 mg tablets.

Please see the full Prescribing Information.